Diagnostic – exudate vs transudate, ?infection, cancer, etc.
Therapeutic or palliative – ↑comfort, ↓nausea, ↑pulmonary fn, ↓effect on venous return
Pre-procedure: FBC, coags ideallydone, but studies show no instances of sig bleeding even if plts<50 & INR>1.5.
Preparation – equipment, explain to patient
Choose site: either lower flank (lateral to inf. Epigastric vessels ~15cm from midline) or in midline 2cm below umbilicus (but beware bladder).
Skin prep & LA
Pull skin caudally or use Z track technique & insert needle (18–22G needle or cannula).
When popped through peritoneum, aspirate should be straw coloured typically.
Withdraw 20–60ml for diagnostic tap or connect to a bag and allow as much as possible to drain over 4–6 hrs for therapeutic tap. Give 100ml albumin for every 1L over 3L drained.
Albumin infusion not normally advised for palliative (Ca) paracentesis but is for cirrhosis as [>3L tap risks hepato-renal syndrome and post-paracentesis circulatory dysfn (PPCD)].
Spironolactone after paracentesis may ↓ repeat rate from >90% to <20% in cirrhosis.
All <2%. Serious Cx as haemoperitoneum and bowel perforation <0.1%
Protein & LDH – for exudate vs transudate. The serum ascites-albumin gradient (SA-AG) is superior: SA-AG = (serum albumin concentration) – (ascitic albumin concentration) where SA-AG <11g/l = Ca, pancreatitis and TB; ≥11g/l = cirrhosis, CCF, nephrotic syn
Avoidance of alcohol is important in pancreatitis and cirrhosis
A no added salt diet, restricted to <90 mmol/day (5.2 g of salt/day) useful in cirrhosis
Spironolactone: ↑sodium excretion and potassium reabsorption in the distal tubules. Initially 100mg/day gradually increased to 400mg as necessary. Monitor K levels Amiloride can be used but it is generally less effective.
Loop diuretics, e.g. frusemide added when max doses of the spironolactone reached. Start with 40mg/day although up to 160mg/day may be used – watch electrolytes.
If the underlying problem is CCF then treatment aggressively with usual Rx.
Malignancy may respond to appropriate chemotherapy, depending upon the type.
Myxoedema will resolve with gradual introduction of thyroxine.
For malignancy and some patients may be suitable for liver transplantation.