ECG of the Week 4th August 2021

A 60 year old male presents with an overdose. Below is the patients ECG:

Describe and interpret the ECG

What drugs can cause these changes on an ECG

Answer:

Rate: 90 beats/min

Rhythm: Normal sinus

Axis: Normal

Intervals

  • PR 200ms
  • QRS 140ms
  • QTc 400ms (Bazettes)

Additional:

RBBB morphology

Dominant R wave aVR

Artefact

The above ECG shows signs of sodium channel blockade – near tachycardia, prolonged QRS and terminal R wave >3mm

Drugs that cause sodium channel blockade include:

TCA

Class 1a and 1c antidysrhythmic agents

Local Anaesthetics

Diltiazam

Propranolol

Hydroxychloroquine

Chloroquine

Quinine

Carbamazepine

Phenothiazines

 

ECG from John Larkins ECG of the Week 18th Feb 2019

Further Reading Toxicology Hand Book Murray,L et al