Lab Case 76 – Interpretation

8 year old male with signs and symptoms of chest infection/ Pneumonia1. Normal FBC, UEC and CRP

Positive cold agglutinins

2. In context of patients presentation, this is likely to indicate a Mycoplasma Pneumonia

Other DDx: Lymphoproliferative disorders, haemolytic disease

3. Bedside:  UA – haematuria, signs of heamolysis


Haemolytic screen – LDH (elevated in this patient – 612), haptoglobin, Coombs test, cryoglobulins

Blood Cultures

Mycoplasma IgM and IgG

Blood Cultures


 Age Pathogen Treatment
 Neonate Grp B strep, E Coli, Listeria (rare)

Atypicals – Chlamydia, Ureaplasma

 Admission, +/- macrolides
 1-3 months Viral

Rarely: Grp B Strep, S.Pnm, S aureus

S. Pyogenes, H Influenza

Atypicals – Chlamydia, Ureaplasma

Admission, +/- macrolides
 <5 S Pneumonia

Other: S Pyogenes, S aureus, H Influenza

Moraxella Catarrhalis

Atypicals – Mycoplasma, Chlamydia

Antibiotics, +/- admission
 >5 Atypicals more likely, same as <5 As above