The daily educational pearl – Cholinergic syndrome

Signs and symptoms of cholinergic syndrome

SLUDGE is the usual mnemonic used. And “the 3 killer Bs”. But I don’t like mnemonics. So if we start from head and go down:

CNS depression / coma

seizures

lacrimation

miosis

salivation

bronchorea / pulmonary oedema

bronchospasm

bradycardia

vomiting

abdominal pain / cramps

muscular weakness / fasciculations

urinary incontinence

diarrhoea / faecal incontinence