Critically unwell 58 year old with life threatening bleeding due to epistaxis. Significant airway and resuscitation concerns. Consider other sources of bleeding, including Oesophageal varices, Peptic ulcer disease etc.
1. Describe and Interpret
Anaemia – likely due to acute haemorrhage
Severe coagulopathy without lab evidence of DIC – high INR, low fibrinogen with normal aPTT, d-dimer and low normal Platelets
Platelets are low normal but with potentially poor functional capacity
Cause – severe liver disease due to alcohol as well as nutritional Vitamen K deficiency
2. Outline your steps in management
This patient requires simultaneous resuscitation and heamorrhage control:
Resuscitation
ABC approach
– Airway, Breathing – ensure airway patency, maintain oxygenation (risk of aspiration)
– Circulation – initial ivi fluids, followed by blood if shocked (O-ve until crossmatch available)
– correct coagulopathy – Vitamen K 10mg with FFP (4 units), Cryoprecipitate, Prothrombin X
– correct electrolytes, calcium
– correct acid-base status
– keep patient warm
– monitor response and fluid status
Haemorrhage control
– Nasal packing
– Immediate ENT consult for ongoing bleeding
3. Key steps in nasal packing
PPE
Local Anaesthetic/ vasoconstrictor
Haemorrhage control – Rapid rhino/ foley’s catheter
Analgesia/ sedation (with care) – titrated morphine / Midazolam
4. Main issues with regard to Aortic stenosis
Volume dependant, fixed outflow obstruction
rate limiting factor for cardiac output – tachycardia with fixed outflow obstruction
Aims
– replace volume to restore circulation to vital organs (cerebral perfusion, HR < 100, SBP >100, MAP > 65-70), optimise prior to surgery
– avoid over resuscitation, replace blood slowly after initial stabilisation, monitor for signs of fluid overload (SOB, falling Oxygen saturation, tachypnoea)
– address coagulopathy
– notify Anaesthetics of Aortic stenosis if going to theatre
Adapted from 2009 fellowship examination on ACEM website
http://en.wikipedia.org/wiki/Heyde's_syndrome Could be considered as a differential in this case
Heyde’s syndrome is intestinal angiodysplasia and bleeding due to type 2 vW disease in patients with severe aortic stenosis. Unlikely in this case but a good thought. A diagnosis often missed in elderly patients with GI bleeds.