paper of the week

Effect of a Diagnostic Strategy Using an Elevated and Age-Adjusted D-Dimer Threshold on Thromboembolic Events in Emergency Department Patients With Suspected Pulmonary Embolism

JAMA. 2021;326(21):2141-2149. doi:10.1001/jama.2021.20750


  • Combination of PERC, YEARS and age adjusted DDimer has been reviewed regarding the use of advacnced imaging and detection of PE in comparison to the classical pathway (definition below)

Bottom line

  • Inclusion of YEARS criteria in workup of VTE patients can be valuable to reduce chest imaging
  • This study is not specific for pregnant patients, further clinical trials will be required

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