51 year old ciritically unwell man with shock and encephalopathy
His blood results show:
Mild thrombocytopaenia – alcohol, additional platelet dysfunction and coagulopathy likely
Elevated inflammatory markers – sepsis, liver failure
Liver failure secondary to alcohol abuse – AST:ALT 2:1, GGT increase >>>ALP increase, mild transaminitis
Reduced albumin – chronic nutritional and synthetic dysfunction of liver (in cirrhosis, often expect increased globulins)
Mild hyponatraemia – liver failure, ascites
Moderate to severe hypokalaemia – diarrhoea and vomiting
Hypochloraemic alkalosis – vomiting
Renal fai;lure – pre renal, ?hepatorenal
Examination Findings:
Vitals – RR, Temp
glucose, ketones
signs of chronic liver disease, cirrhosis, portal hypertension
Complications -sepsis, SBP etc
Ppt factors for encephalopathy – D and V, drugs, sepsis etc